Basic Information
ID: ALA4360961
Type: Binding
Description: Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activation at -100 mV holding potential treated for 1 min by two electrode voltage-clamp assay relative to PhTX-343 IC50
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4360961
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.61 | 1.33 | 1.33 |
| 433.64 | 1.72 | 1.72 |
| 535.78 | 4.24 | 4.24 |
| 523.77 | 3.65 | 3.65 |
| 425.66 | 2.06 | 2.06 |
| 423.65 | 1.67 | 1.67 |
| 465.73 | 2.84 | 2.84 |
| 491.77 | 3.08 | 3.08 |
| 479.75 | 3.23 | 3.23 |
| 459.68 | 2.57 | 2.57 |
| 485.72 | 2.97 | 2.97 |
| 451.70 | 2.45 | 2.45 |
| 447.62 | 0.89 | 0.89 |
| 447.62 | 0.89 | 0.89 |
| 475.68 | 1.81 | 1.81 |
| 437.67 | 2.06 | 2.06 |
| 461.65 | 1.42 | 1.42 |