Assay Report Card

Basic Information

ID: ALA4361387

Type: Binding

Description: Inhibition of PCSK9 (unknown origin) interaction with LDLR expressed in human HepG2 cells assessed as LDLR level on cell membrane at 1 uM measured after 2 hrs by in-cell Western analysis (Rvb = 30.5 to 47.2%)

Organism: Homo sapiens

Cell type: HepG2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1108.26
509.665.265.26