Assay Report Card

Basic Information

ID: ALA4361571

Type: Binding

Description: Antagonist activity at TLR4 in mouse RAW264.7 cells assessed as reduction in LPS-induced NFkappaB p65 phosphorylation at 80 uM preincubated for 1 hr followed by LPS stimulation and measured after 30 mins by Alexafluor-488/Hoechst 33258 staining based immunofluorescence confocal microscopic method

Organism: Mus musculus

Cell type: RAW264.7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1434.75