Basic Information
ID: ALA4361677
Type: Binding
Description: Inhibition of ALK5 in human LX2 cells assessed as reduction in TGFbeta-induced alphaSMA production at 5 uM pretreated for 1 hr followed by TGFbeta addition and measured after 12 hrs by DAPI staining based immunocytochemistry analysis by confocal laser scanning microscopic method
Format: BAO_0000219
Organism: Homo sapiens
Target: TGF-beta receptor type I(ALA4439)
Document: ALA4359846
Inhibition of ALK5 in human LX2 cells assessed as reduction in TGFbeta-induced alphaSMA production at 5 uM pretreated for 1 hr followed by TGFbeta addition and measured after 12 hrs by DAPI staining based immunocytochemistry analysis by confocal laser scanning microscopic method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4361677
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.43 | 3.51 | 3.51 |