Basic Information
ID: ALA4361678
Type: Binding
Description: Inhibition of ALK5 in human LX2 cells assessed as reduction in TGFbeta-induced collagen 1 protein expression at 1.25 to 5 uM pretreated for 1 hr followed by TGFbeta addition and measured after 12 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: TGF-beta receptor type I(ALA4439)
Document: ALA4359846
Inhibition of ALK5 in human LX2 cells assessed as reduction in TGFbeta-induced collagen 1 protein expression at 1.25 to 5 uM pretreated for 1 hr followed by TGFbeta addition and measured after 12 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4361678
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 460.56 | 5.50 | 5.50 |
| 425.52 | 5.17 | 5.17 |