Basic Information
ID: ALA4361836
Type: Binding
Description: Inhibition of CRM1 in human HepG2 cells assessed as upregulation of p53 by measuring accumulation in nucleus at 0.1 to 10 uM measured after 6 to 24 hrs by DAPI staining based immunofluorescence microscopy analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HepG2
Target: Exportin-1(ALA5661)
Document: ALA4359853
Inhibition of CRM1 in human HepG2 cells assessed as upregulation of p53 by measuring accumulation in nucleus at 0.1 to 10 uM measured after 6 to 24 hrs by DAPI staining based immunofluorescence microscopy analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4361836
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 238.29 | 3.69 | 3.69 |