Basic Information
ID: ALA4361889
Type: Binding
Description: Protac activity at VHL/IRAK4 in human PBMC assessed as reduction in R848-stimulated IL-6 level preincubated for 18 hrs followed by R848 stimulation and measured after 8 hrs by MSD assay
Format: BAO_0000224
Organism: Homo sapiens
Target: VHL/IRAK4(ALA4523742)
Document: ALA4359855
Protac activity at VHL/IRAK4 in human PBMC assessed as reduction in R848-stimulated IL-6 level preincubated for 18 hrs followed by R848 stimulation and measured after 8 hrs by MSD assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4361889
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 361.37 | 1.58 | 1.58 |
| 1086.30 |