Basic Information
ID: ALA4361892
Type: Binding
Description: Protac activity at VHL/IRAK4 in human PBMC assessed as reduction in R848-stimulated TNFalpha level preincubated for 18 hrs followed by R848 stimulation and measured after 8 hrs by MSD assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4361892
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 361.37 | 1.58 | 1.58 |
| 1086.30 |