Basic Information
ID: ALA4361899
Type: Binding
Description: Protac activity at VHL/IRAK4 in human THP-1 cells assessed as induction of degradation of IRAK4 at 0.1 to 10 uM incubated for 24 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: VHL/IRAK4(ALA4523742)
Document: ALA4359855
Protac activity at VHL/IRAK4 in human THP-1 cells assessed as induction of degradation of IRAK4 at 0.1 to 10 uM incubated for 24 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4361899
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 995.19 | 2.74 | 2.74 |
| 751.84 | 4.34 | 4.34 |
| 757.75 | 0.88 | 0.88 |
| 838.00 | 3.76 | 3.76 |
| 823.97 | 3.37 | 3.37 |
| 942.11 | 3.03 | 3.03 |
| 989.27 | 6.20 | 6.20 |