Assay Report Card

Basic Information

ID: ALA4361899

Type: Binding

Description: Protac activity at VHL/IRAK4 in human THP-1 cells assessed as induction of degradation of IRAK4 at 0.1 to 10 uM incubated for 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: THP-1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
995.192.742.74
751.844.344.34
757.750.880.88
838.003.763.76
823.973.373.37
942.113.033.03
989.276.206.20