Basic Information
ID: ALA4361991
Type: ADME
Description: Inhibition of human recombinant AChE expressed in HEK293 cells using acetylcholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and measured after 5 mins by Ellman's method
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4361991
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 198.27 | 2.70 | 2.70 |
| 302.38 | 4.57 | 4.57 |
| 418.58 | 5.96 | 5.96 |
| 334.38 | 3.98 | 3.98 |
| 404.55 | 5.66 | 5.66 |
| 320.39 | 4.14 | 4.14 |
| 318.38 | 4.28 | 4.28 |
| 600.80 | 9.11 | 9.11 |
| 448.61 | 5.97 | 5.97 |
| 419.57 | 5.29 | 5.29 |
| 494.68 | 7.53 | 7.53 |
| 420.55 | 5.37 | 5.37 |