Microsomal stability in human liver microsomes assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM and measured for 30 mins in...

Basic Information

ID: ALA4362184

Type: ADME

Description: Microsomal stability in human liver microsomes assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM and measured for 30 mins in presence of UDPGA by UPLC-MS/MS analysis (Rvb = 100%)

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  UDP-glucuronosyltransferases (UGTs)(ALA4523985)

Document:  ALA4359864

Microsomal stability in human liver microsomes assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM and measured for 30 mins in presence of UDPGA by UPLC-MS/MS analysis (Rvb = 100%): 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
296.154.364.36
343.304.364.36
275.313.343.34
343.304.364.36
293.303.483.48
293.303.483.48
293.303.483.48