Basic Information
ID: ALA4362208
Type: Binding
Description: Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system using FAM-22 peptide as substrate incubated for 10 mins followed by substrate addition by caliper method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4362208
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 475.36 | 4.43 | 4.43 |
| 649.43 | 3.01 | 3.01 |
| 561.33 | 2.98 | 2.98 |
| 526.49 | 2.23 | 2.23 |
| 557.37 | 3.15 | 3.15 |
| 614.43 | 4.71 | 4.71 |
| 588.53 | 2.39 | 2.39 |
| 595.38 | 3.54 | 3.54 |
| 560.93 | 2.89 | 2.89 |
| 605.38 | 3.00 | 3.00 |
| 604.98 | 2.90 | 2.90 |
| 645.47 | 3.18 | 3.18 |
| 516.88 | 2.87 | 2.87 |
| 601.42 | 3.16 | 3.16 |
| 526.49 | 2.23 | 2.23 |
| 544.48 | 2.37 | 2.37 |