Drug metabolism in human liver microsomes assessed as oxidative N-dealkylation at 50 uM measured after 60 mins in absence of NADPH by LC-ESI/MS analys...

Basic Information

ID: ALA4362394

Type: ADME

Description: Drug metabolism in human liver microsomes assessed as oxidative N-dealkylation at 50 uM measured after 60 mins in absence of NADPH by LC-ESI/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target: ADMET(ALA612558)

Document: ALA4359872

Drug metabolism in human liver microsomes assessed as oxidative N-dealkylation at 50 uM measured after 60 mins in absence of NADPH by LC-ESI/MS analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4362394

Drug metabolism

Total(1)

Parent Molecular Weight	ALogP	Polar Surface Area
439.56	5.39	5.39

Parent Molecular Weight

ALogP

Polar Surface Area

439.56

5.39

Drug metabolism in human liver microsomes assessed as oxidative N-dealkylation at 50 uM measured after 60 mins in absence of NADPH by LC-ESI/MS analys...

Basic Information

Activity Charts

Compound Summary