Basic Information
ID: ALA4362531
Type: Binding
Description: Inhibition of N-terminal His-tagged human JAK2 catalytic domain (826 to 1132 resiudes) expressed in baculovirus expression system using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition measured after 1 hr in presence of ATP by mobility shift assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Tyrosine-protein kinase JAK2(ALA2971)
Document: ALA4359878
Inhibition of N-terminal His-tagged human JAK2 catalytic domain (826 to 1132 resiudes) expressed in baculovirus expression system using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition measured after 1 hr in presence of ATP by mobility shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4362531
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 502.58 | 2.51 | 2.51 |
| 517.66 | 4.33 | 4.33 |
| 543.67 | 4.64 | 4.64 |
| 514.63 | 3.53 | 3.53 |
| 538.63 | 2.06 | 2.06 |
| 501.59 | 3.61 | 3.61 |