Basic Information
ID: ALA4362639
Type: Functional
Description: Antiamoebic activity against Acanthamoeba castellanii T4 genotype ATCC 50492 infected in human HaCaT cells assessed as reduction in amoeba-induced host cell cytopathogenicity at 100 ug/ml preincubated with amoeba for 2 hrs followed by incubation of suspension with host cell for 24 hrs by LDH release assay
Organism: Acanthamoeba castellanii
Strain: T4 genotype ATCC 50492
Activity Charts
Bioactivity
Activity Types for Assay ALA4362639
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 272.25 | 2.97 | 2.97 |
| 254.26 | 2.83 | 2.83 |
| 264.33 | 3.31 | 3.31 |
| 270.72 | 3.35 | 3.35 |
| 270.72 | 3.35 | 3.35 |
| 250.30 | 3.00 | 3.00 |
| 266.30 | 2.70 | 2.70 |
| 296.33 | 2.71 | 2.71 |
| 282.37 | 3.42 | 3.42 |
| 315.17 | 3.46 | 3.46 |
| 315.17 | 3.46 | 3.46 |