Basic Information
ID: ALA4362816
Type: Binding
Description: Displacement of 5'FAM-LTFEHYWAQLTS from human recombinant N-terminal domain of MDM2 (1 to 118 residues) expressed in Escherichia coli BL21 (DE3) cells measured after 15 mins by fluorescence polarization assay
Format: BAO_0000219
Organism: Homo sapiens
Target: p53-binding protein Mdm-2(ALA5023)
Document: ALA4359887
Displacement of 5'FAM-LTFEHYWAQLTS from human recombinant N-terminal domain of MDM2 (1 to 118 residues) expressed in Escherichia coli BL21 (DE3) cells measured after 15 mins by fluorescence polarization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4362816
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 581.50 | 5.89 | 5.89 |
| 441.92 | 4.13 | 4.13 |
| 582.48 | 6.37 | 6.37 |
| 598.93 | 6.61 | 6.61 |
| 705.05 | 7.65 | 7.65 |
| 593.04 | 5.62 | 5.62 |
| 562.07 | 6.02 | 6.02 |
| 549.03 | 5.11 | 5.11 |
| 566.03 | 5.85 | 5.85 |
| 626.94 | 6.48 | 6.48 |
| 584.02 | 5.99 | 5.99 |
| 640.96 | 6.52 | 6.52 |
| 684.03 | 7.75 | 7.75 |
| 616.93 | 7.02 | 7.02 |
| 673.94 | 6.32 | 6.32 |
| 578.07 | 5.72 | 5.72 |
| 673.94 | 6.32 | 6.32 |
| 533.88 | 6.84 | 6.84 |
| 478.98 | 2.66 | 2.66 |
| 566.03 | 5.85 | 5.85 |
| 612.95 | 6.95 | 6.95 |
| 526.03 | 5.46 | 5.46 |
| 626.94 | 6.48 | 6.48 |
| 573.05 | 5.58 | 5.58 |
| 393.31 | 4.61 | 4.61 |
| 503.99 | 4.62 | 4.62 |
| 554.07 | 5.77 | 5.77 |
| 707.07 | 7.89 | 7.89 |
| 582.48 | 6.37 | 6.37 |
| 644.14 | 7.02 | 7.02 |
| 566.03 | 5.85 | 5.85 |
| 606.09 | 6.78 | 6.78 |
| 616.93 | 7.02 | 7.02 |
| 626.94 | 6.48 | 6.48 |
| 640.18 | 7.27 | 7.27 |
| 616.04 | 6.73 | 6.73 |
| 707.07 | 7.89 | 7.89 |
| 616.93 | 7.02 | 7.02 |
| 584.02 | 5.99 | 5.99 |
| 598.10 | 6.87 | 6.87 |
| 554.09 | 6.09 | 6.09 |
| 705.05 | 7.50 | 7.50 |
| 624.14 | 7.38 | 7.38 |
| 626.94 | 6.48 | 6.48 |
| 626.94 | 6.48 | 6.48 |
| 534.06 | 5.35 | 5.35 |
| 582.12 | 6.25 | 6.25 |
| 549.03 | 5.11 | 5.11 |
| 548.04 | 5.71 | 5.71 |
| 549.03 | 5.11 | 5.11 |
| 739.11 | 5.84 | 5.84 |
| 582.48 | 6.37 | 6.37 |
| 673.94 | 6.32 | 6.32 |
| 654.01 | 6.99 | 6.99 |
| 562.07 | 5.76 | 5.76 |
| 640.96 | 6.49 | 6.49 |
| 625.95 | 6.51 | 6.51 |
| 608.09 | 5.73 | 5.73 |