Basic Information
ID: ALA4362821
Type: Binding
Description: Inhibition of MDM2-p53 interaction in human U2OS cells expressing wild-type p53 assessed as upregulation of p21 expression at 20 to 50 uM measured after 24 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: U2OS
Target: Tumour suppressor p53/oncoprotein Mdm2(ALA1907611)
Document: ALA4359887
Inhibition of MDM2-p53 interaction in human U2OS cells expressing wild-type p53 assessed as upregulation of p21 expression at 20 to 50 uM measured after 24 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4362821
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 707.07 | 7.89 | 7.89 |
| 705.05 | 7.50 | 7.50 |
| 626.94 | 6.48 | 6.48 |