Basic Information
ID: ALA4362827
Type: Functional
Description: Induction of apoptosis in human HCT116 cells expressing wild type p53 assessed as necrotic cells at 20 uM measured after 72 hrs by annexin V-FITC/propidium iodide staining-based flow cytometry analysis (Rvb = 0.7 %)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HCT-116
Target: HCT-116(ALA394)
Document: ALA4359887
Induction of apoptosis in human HCT116 cells expressing wild type p53 assessed as necrotic cells at 20 uM measured after 72 hrs by annexin V-FITC/propidium iodide staining-based flow cytometry analysis (Rvb = 0.7 %): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4362827
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 581.50 | 5.89 | 5.89 |
| 590.12 | 6.50 | 6.50 |
| 562.07 | 6.02 | 6.02 |
| 701.99 | 6.80 | 6.80 |
| 626.94 | 6.48 | 6.48 |
| 673.94 | 6.32 | 6.32 |
| 578.07 | 5.72 | 5.72 |
| 644.98 | 7.50 | 7.50 |
| 590.12 | 6.23 | 6.23 |
| 654.99 | 6.95 | 6.95 |
| 626.94 | 6.48 | 6.48 |
| 616.93 | 7.02 | 7.02 |
| 584.02 | 5.99 | 5.99 |
| 654.99 | 6.95 | 6.95 |
| 610.54 | 6.84 | 6.84 |
| 606.12 | 6.20 | 6.20 |
| 612.07 | 6.47 | 6.47 |
| 582.48 | 6.37 | 6.37 |
| 654.01 | 6.99 | 6.99 |
| 562.07 | 5.76 | 5.76 |
| 625.95 | 6.51 | 6.51 |