Basic Information
ID: ALA4362836
Type: ADME
Description: Metabolic stability in mouse liver microsomes assessed as half life of compound at 1 uM and measured for 60 mins in presence of NADPH by HPLC-MS/MS analysis
Format: BAO_0000251
Organism: Mus musculus
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4359888
Metabolic stability in mouse liver microsomes assessed as half life of compound at 1 uM and measured for 60 mins in presence of NADPH by HPLC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4362836
T1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 557.47 | 6.32 | 6.32 |
| 557.47 | 6.32 | 6.32 |
| 486.39 | 5.70 | 5.70 |
| 600.54 | 4.83 | 4.83 |
| 487.42 | 5.86 | 5.86 |
| 529.41 | 6.00 | 6.00 |
| 543.44 | 5.93 | 5.93 |
| 626.58 | 5.48 | 5.48 |
| 571.50 | 6.71 | 6.71 |
| 545.46 | 5.88 | 5.88 |
| 545.46 | 5.71 | 5.71 |
| 559.48 | 6.27 | 6.27 |
| 571.50 | 6.71 | 6.71 |
| 612.55 | 5.42 | 5.42 |
| 614.56 | 5.48 | 5.48 |
| 485.41 | 6.30 | 6.30 |
| 545.46 | 5.71 | 5.71 |
| 559.48 | 6.10 | 6.10 |
| 598.52 | 5.03 | 5.03 |
| 603.54 | 6.57 | 6.57 |
| 628.59 | 5.61 | 5.61 |
| 543.44 | 5.93 | 5.93 |
| 573.51 | 6.66 | 6.66 |
| 656.60 | 5.95 | 5.95 |
| 626.57 | 5.81 | 5.81 |
| 662.63 | 4.88 | 4.88 |
| 485.89 | 5.83 | 5.83 |
| 573.51 | 6.49 | 6.49 |
| 486.39 | 5.70 | 5.70 |
| 545.46 | 5.71 | 5.71 |
| 628.55 | 5.17 | 5.17 |