Basic Information
ID: ALA4363350
Type: Binding
Description: Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate addition by enzyme immunoassay
Format: BAO_0000357
Organism: Homo sapiens
Target: Dihydrofolate reductase(ALA202)
Document: ALA4359904
Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate addition by enzyme immunoassay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4363350
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.45 | 0.27 | 0.27 |
| 295.29 | 2.24 | 2.24 |
| 251.28 | 2.55 | 2.55 |
| 587.08 | 6.63 | 6.63 |
| 511.58 | 5.66 | 5.66 |
| 534.57 | 3.60 | 3.60 |
| 367.36 | 1.00 | 1.00 |