Basic Information
ID: ALA4364614
Type: Binding
Description: Inhibition of recombinant TOP1 (unknown origin) using 3'-[32P]-labeled 117 bp DNA oligonucleotide assessed as TOP1-mediated DNA cleavage by measuring induction and stabilization of cleavage sites 17, 35 and 79 incubated for 20 mins by PAGE analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase I(ALA1781)
Document: ALA4364246
Inhibition of recombinant TOP1 (unknown origin) using 3'-[32P]-labeled 117 bp DNA oligonucleotide assessed as TOP1-mediated DNA cleavage by measuring induction and stabilization of cleavage sites 17, 35 and 79 incubated for 20 mins by PAGE analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4364614
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.41 | 3.01 | 3.01 |
| 514.47 | 4.39 | 4.39 |
| 496.54 | 3.14 | 3.14 |
| 541.58 | 2.22 | 2.22 |
| 512.46 | 4.14 | 4.14 |
| 406.44 | 3.27 | 3.27 |