Basic Information
ID: ALA4364957
Type: Binding
Description: Reversible inhibition of Enterovirus 71 3C protease assessed as overall inhibition constant using NMA-IEALFQGPPK(DNP)FR as substrate pre-incubated for 30 mins followed by substrate addition and measured over 30 mins by fluorescence method
Format: BAO_0000019
Organism: Enterovirus A71
Target: Unchecked(ALA612545)
Document: ALA4364253
Reversible inhibition of Enterovirus 71 3C protease assessed as overall inhibition constant using NMA-IEALFQGPPK(DNP)FR as substrate pre-incubated for 30 mins followed by substrate addition and measured over 30 mins by fluorescence method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4364957
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 534.97 | 2.16 | 2.16 |
| 579.42 | 2.32 | 2.32 |
| 544.59 | 2.87 | 2.87 |
| 624.67 | 2.71 | 2.71 |
| 553.59 | 2.27 | 2.27 |
| 611.60 | 4.49 | 4.49 |
| 549.63 | 3.53 | 3.53 |
| 652.72 | 3.49 | 3.49 |
| 538.58 | 1.45 | 1.45 |
| 525.54 | 1.49 | 1.49 |
| 553.59 | 2.27 | 2.27 |
| 593.45 | 2.71 | 2.71 |
| 552.61 | 1.84 | 1.84 |
| 524.55 | 1.06 | 1.06 |
| 638.70 | 3.10 | 3.10 |
| 546.40 | 2.67 | 2.67 |
| 546.60 | 2.96 | 2.96 |
| 501.95 | 2.51 | 2.51 |
| 539.56 | 1.88 | 1.88 |
| 593.66 | 4.62 | 4.62 |
| 543.60 | 3.47 | 3.47 |
| 544.59 | 2.87 | 2.87 |
| 549.00 | 2.55 | 2.55 |
| 549.63 | 3.53 | 3.53 |
| 527.55 | 1.57 | 1.57 |
| 481.53 | 2.33 | 2.33 |
| 567.62 | 2.66 | 2.66 |
| 538.58 | 1.40 | 1.40 |