Assay Report Card

Basic Information

ID: ALA4365267

Type: ADME

Description: Antagonist activity at rat alpha6alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay relative to PeIA logIC50

Organism: Rattus norvegicus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1623.85
1666.91
1678.93
1694.93
1678.97
1701.96
1680.94
1637.87
1665.93
1708.99
1665.93
1651.90
1665.93
1651.90
1637.87
1665.93
1694.97
1728.00
1695.91
1609.82
1650.92
1653.87
1652.88
1693.98
1665.93