Basic Information
ID: ALA4365545
Type: Binding
Description: Inhibition of recombinant N-terminal His-tagged human ERK5 (2 to 409 residues) co-expressed with GST-tagged human truncated MEK5DD lacking N-terminal 11 residues (13 to 448 residues) in Sf9 insect cells assessed as substrate peptide phosphorylation using (LVEPLTPSGEAPNQ(K-5FAM)-COOH as substrate incubated for 2 hrs by IMAP fluorescence polarisation assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4365545
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 388.20 | 3.79 | 3.79 |
| 327.29 | 3.17 | 3.17 |
| 341.32 | 2.85 | 2.85 |
| 374.23 | 3.88 | 3.88 |
| 343.75 | 3.69 | 3.69 |
| 341.32 | 2.85 | 2.85 |
| 339.78 | 3.22 | 3.22 |
| 327.29 | 3.17 | 3.17 |
| 339.78 | 3.22 | 3.22 |
| 323.33 | 2.71 | 2.71 |
| 388.20 | 3.79 | 3.79 |
| 343.75 | 3.69 | 3.69 |
| 323.33 | 2.71 | 2.71 |
| 305.34 | 2.57 | 2.57 |
| 339.78 | 3.22 | 3.22 |
| 323.33 | 2.71 | 2.71 |