Basic Information
ID: ALA4366088
Type: ADME
Description: Stability in mouse liver microsomes assessed as parent compound remaining at 50 uM preincubated for 5 to 7 mins followed by NADPH addition and measured 10 mins post-dose by LC-MS/MS
Format: BAO_0000251
Organism: Mus musculus
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4364272
Stability in mouse liver microsomes assessed as parent compound remaining at 50 uM preincubated for 5 to 7 mins followed by NADPH addition and measured 10 mins post-dose by LC-MS/MS: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4366088
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 602.86 | 6.74 | 6.74 |
| 707.51 | 6.81 | 6.81 |
| 638.53 | 5.84 | 5.84 |
| 665.89 | 5.90 | 5.90 |
| 642.51 | 6.81 | 6.81 |
| 706.52 | 6.77 | 6.77 |
| 628.48 | 6.37 | 6.37 |
| 692.54 | 7.25 | 7.25 |
| 720.55 | 7.16 | 7.16 |
| 600.43 | 5.77 | 5.77 |
| 618.86 | 5.71 | 5.71 |
| 614.46 | 6.03 | 6.03 |
| 693.53 | 7.28 | 7.28 |
| 704.51 | 6.53 | 6.53 |