Basic Information
ID: ALA4366119
Type: Functional
Description: Antagonist activity at human OTR expressed in HEK293 cells assessed as decrease in calcium flux measured after 10 mins in presence of vasopressin by Fluo-4 dye based microplate reader based assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4366119
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.84 | 2.88 | 2.88 |
| 518.66 | 2.76 | 2.76 |
| 442.88 | 3.71 | 3.71 |
| 473.94 | 4.19 | 4.19 |
| 444.90 | 2.93 | 2.93 |
| 431.90 | 3.99 | 3.99 |
| 429.88 | 3.39 | 3.39 |
| 443.91 | 3.78 | 3.78 |
| 417.87 | 3.60 | 3.60 |
| 397.41 | 2.20 | 2.20 |
| 429.88 | 3.39 | 3.39 |
| 473.94 | 3.90 | 3.90 |
| 461.90 | 3.73 | 3.73 |
| 435.84 | 4.18 | 4.18 |
| 485.95 | 3.55 | 3.55 |
| 425.90 | 4.12 | 4.12 |
| 445.93 | 3.99 | 3.99 |
| 459.91 | 3.01 | 3.01 |
| 429.88 | 3.39 | 3.39 |
| 424.87 | 3.31 | 3.31 |
| 411.44 | 2.54 | 2.54 |
| 446.91 | 2.93 | 2.93 |
| 499.97 | 3.94 | 3.94 |
| 485.95 | 3.55 | 3.55 |
| 429.88 | 3.39 | 3.39 |
| 444.90 | 2.93 | 2.93 |