Basic Information
ID: ALA4366681
Type: Binding
Description: Inhibition of HGF-induced cMET autophosphorylation in human MKN45 cells preincubated for 1 hr followed by HGF addition and measured after 10 mins by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Target: Hepatocyte growth factor receptor(ALA3717)
Document: ALA4364278
Inhibition of HGF-induced cMET autophosphorylation in human MKN45 cells preincubated for 1 hr followed by HGF addition and measured after 10 mins by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4366681
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 512.90 | 5.19 | 5.19 |
| 552.54 | 6.77 | 6.77 |
| 487.92 | 6.00 | 6.00 |
| 505.91 | 6.14 | 6.14 |
| 615.35 | 6.23 | 6.23 |
| 553.53 | 6.16 | 6.16 |
| 597.36 | 6.09 | 6.09 |
| 571.92 | 6.90 | 6.90 |
| 579.37 | 5.95 | 5.95 |
| 472.46 | 4.76 | 4.76 |
| 498.45 | 5.18 | 5.18 |
| 491.89 | 5.83 | 5.83 |
| 498.51 | 6.81 | 6.81 |
| 583.34 | 5.78 | 5.78 |
| 499.50 | 6.20 | 6.20 |
| 523.90 | 6.28 | 6.28 |
| 522.37 | 6.65 | 6.65 |