ID: ALA4366767
Type: Functional
Description: Antagonist activity at recombinant human 5HT6 receptor expressed in CHOK1 cells co-expressing Galpha16/aequorin assessed as reduction in serotonin-induced calcium mobilization flux preincubated for 30 mins followed by serotonin addition in presence of coelenterazine h by luminescence assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4366767
Kb
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
264.37 | 3.08 | 3.08 |
176.22 | 1.37 | 1.37 |
353.45 | 2.48 | 2.48 |
348.84 | 2.00 | 2.00 |
364.91 | 2.71 | 2.71 |
356.47 | 2.22 | 2.22 |