Basic Information
ID: ALA4366856
Type: Binding
Description: Inhibition of recombinant human COX-2 assessed as reduction in prostaglandin production preincubated for 10 mins followed by arachidonic acid addition and measured after 2 mins by EIA method
Format: BAO_0000357
Organism: Homo sapiens
Target: Cyclooxygenase-2(ALA230)
Document: ALA4364282
Inhibition of recombinant human COX-2 assessed as reduction in prostaglandin production preincubated for 10 mins followed by arachidonic acid addition and measured after 2 mins by EIA method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4366856
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.79 | 3.93 | 3.93 |
| 381.38 | 3.51 | 3.51 |
| 519.56 | -0.80 | -0.80 |
| 442.47 | -3.65 | -3.65 |
| 328.37 | -1.88 | -1.88 |
| 385.42 | -2.77 | -2.77 |
| 362.43 | 2.20 | 2.20 |
| 391.42 | 0.58 | 0.58 |
| 685.78 | 2.04 | 2.04 |
| 377.40 | 0.49 | 0.49 |
| 564.71 | 1.64 | 1.64 |
| 598.72 | 2.04 | 2.04 |