Basic Information
ID: ALA4367123
Type: Functional
Description: Inhibition of M-CSF/RANKL-induced osteoclast differentiation in C57BL/6 mouse bone marrow macrophage assessed as reduction in multinucleated TRAP+ cells incubated for 6 days with fresh media replacement on day 3 and measured on day 6 by TRAP staining-based microscopic analysis
Format: BAO_0000219
Organism: Mus musculus
Strain: C57BL/6
Cell type: BMDM
Target: Unchecked(ALA612545)
Document: ALA4364291
Inhibition of M-CSF/RANKL-induced osteoclast differentiation in C57BL/6 mouse bone marrow macrophage assessed as reduction in multinucleated TRAP+ cells incubated for 6 days with fresh media replacement on day 3 and measured on day 6 by TRAP staining-based microscopic analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4367123
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 162.19 | 1.99 | 1.99 |
| 271.08 | -1.27 | -1.27 |
| 180.16 | 1.20 | 1.20 |
| 148.16 | 1.78 | 1.78 |
| 354.31 | -0.65 | -0.65 |
| 154.12 | 0.80 | 0.80 |
| 178.19 | 1.70 | 1.70 |
| 136.15 | 1.31 | 1.31 |
| 192.21 | 2.00 | 2.00 |
| 192.21 | 2.00 | 2.00 |
| 168.15 | 0.72 | 0.72 |
| 138.12 | 0.91 | 0.91 |
| 354.31 | -0.65 | -0.65 |
| 168.15 | 0.88 | 0.88 |
| 182.18 | 0.81 | 0.81 |
| 181.17 | 1.03 | 1.03 |
| 180.18 | 2.13 | 2.13 |
| 268.31 | 3.57 | 3.57 |
| 176.21 | 2.30 | 2.30 |
| 180.18 | 2.13 | 2.13 |
| 177.20 | 1.20 | 1.20 |
| 218.25 | 2.56 | 2.56 |
| 220.27 | 2.78 | 2.78 |