Basic Information
ID: ALA4367190
Type: Binding
Description: Antagonist activity at CCR4 in human CCRF-CEM cells assessed as inhibition of CCL22-mediated chemotaxis in presence of 100% human serum pre-incubated for 30 mins followed by CCL22 addition and measured after 60 mins by chemoTX probe based CellTiter-Glo assay
Organism: Homo sapiens
Cell type: CCRF-CEM
Activity Charts
Bioactivity
Activity Types for Assay ALA4367190
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 500.47 | 5.69 | 5.69 |
| 487.48 | 5.75 | 5.75 |
| 579.60 | 5.16 | 5.16 |
| 517.46 | 4.81 | 4.81 |
| 510.47 | 5.22 | 5.22 |
| 511.46 | 5.25 | 5.25 |
| 549.43 | 6.82 | 6.82 |
| 501.51 | 6.14 | 6.14 |
| 487.48 | 5.75 | 5.75 |
| 580.59 | 4.41 | 4.41 |
| 495.46 | 6.28 | 6.28 |
| 524.46 | 4.75 | 4.75 |
| 526.52 | 6.03 | 6.03 |
| 539.51 | 6.03 | 6.03 |
| 459.43 | 4.97 | 4.97 |
| 514.46 | 4.29 | 4.29 |
| 473.45 | 5.36 | 5.36 |
| 503.48 | 4.72 | 4.72 |
| 544.53 | 5.00 | 5.00 |
| 487.48 | 5.75 | 5.75 |
| 516.48 | 4.22 | 4.22 |