Basic Information
ID: ALA4367206
Type: Binding
Description: Antagonist activity at CCR4 in anti-CD3/CD28 stimulated mouse Treg cells assessed as inhibition of CCL22-mediated chemotaxis in presence of 100% human serum pre-incubated for 30 mins followed by CCL22 addition and measured after 60 mins by chemoTX probe based CellTiter-Glo assay
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4367206
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 511.46 | 5.25 | 5.25 |
| 495.46 | 6.28 | 6.28 |