Prodrug conversion in Sprague-Dawley rat hepatic portal vein assessed as 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)e...

Basic Information

ID: ALA4367394

Type: ADME

Description: Prodrug conversion in Sprague-Dawley rat hepatic portal vein assessed as 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethanol formation

Format: BAO_0000221

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Tissue: Hepatic portal vein

Target:  ADMET(ALA612558)

Document:  ALA4364295

Prodrug conversion in Sprague-Dawley rat hepatic portal vein assessed as 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethanol formation: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
557.704.464.46
580.644.044.04