Basic Information
ID: ALA4367495
Type: ADME
Description: Prodrug conversion in minipig hepatocytes assessed as (2S,3S,4S,5R,6R)-6-(2-(4-(benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yloxy)ethoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid formation at 20 uM measured after 4 hrs
Format: BAO_0000219
Organism: Sus scrofa
Cell type: Hepatocyte
Target: ADMET(ALA612558)
Document: ALA4364295
Prodrug conversion in minipig hepatocytes assessed as (2S,3S,4S,5R,6R)-6-(2-(4-(benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yloxy)ethoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid formation at 20 uM measured after 4 hrs: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4367495
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 580.64 | 4.04 | 4.04 |