Prodrug conversion in minipig hepatocytes assessed as 2-(4-(benzo[d]thiazol-5-ylamino)-7-(2-hydroxyethoxy)quinazolin-6-ylsulfonyl)-2-methylpropan-1-ol...

Basic Information

ID: ALA4367496

Type: ADME

Description: Prodrug conversion in minipig hepatocytes assessed as 2-(4-(benzo[d]thiazol-5-ylamino)-7-(2-hydroxyethoxy)quinazolin-6-ylsulfonyl)-2-methylpropan-1-ol formation at 20 uM measured after 4 hrs

Format: BAO_0000219

Organism: Sus scrofa

Cell type: Hepatocyte

Target:  ADMET(ALA612558)

Document:  ALA4364295

Prodrug conversion in minipig hepatocytes assessed as 2-(4-(benzo[d]thiazol-5-ylamino)-7-(2-hydroxyethoxy)quinazolin-6-ylsulfonyl)-2-methylpropan-1-ol formation at 20 uM measured after 4 hrs: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
580.644.044.04