Basic Information
ID: ALA4368012
Type: Functional
Description: Inhibition of 8-OH-DPAT-induced hypothermia in CD-1 mouse assessed change in body temperature at 20 mg/kg, ip pretreated for 45 mins followed by 8-OH-DPAT addition and measured after 60 mins by thermometric method (Rvb = -2.8 to -0.6 deg C)
Format: BAO_0000218
Organism: Mus musculus
Strain: CD-1
Target: Mus musculus(ALA375)
Document: ALA4364313
Inhibition of 8-OH-DPAT-induced hypothermia in CD-1 mouse assessed change in body temperature at 20 mg/kg, ip pretreated for 45 mins followed by 8-OH-DPAT addition and measured after 60 mins by thermometric method (Rvb = -2.8 to -0.6 deg C): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4368012
deltaT
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 514.65 | 5.29 | 5.29 |
| 531.10 | 5.81 | 5.81 |
| 514.65 | 5.29 | 5.29 |
| 496.66 | 5.15 | 5.15 |
| 532.64 | 5.43 | 5.43 |