Basic Information
ID: ALA4368067
Type: Binding
Description: Corrector activity at CFTR F508del mutant (unknown origin) expressed in rat FRT cells assessed as Vmax preincubated for 18 to 24 hrs followed by compound wash out and addition of forskolin and genistein by fluorescence based assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Cystic fibrosis transmembrane conductance regulator(ALA4051)
Document: ALA4364316
Corrector activity at CFTR F508del mutant (unknown origin) expressed in rat FRT cells assessed as Vmax preincubated for 18 to 24 hrs followed by compound wash out and addition of forskolin and genistein by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4368067
Vmax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 390.44 | 3.27 | 3.27 |
| 390.44 | 3.27 | 3.27 |
| 374.44 | 3.57 | 3.57 |
| 422.51 | 2.93 | 2.93 |
| 390.42 | 3.22 | 3.22 |
| 350.45 | 3.63 | 3.63 |