Basic Information
ID: ALA4368069
Type: Binding
Description: Potentiator activity at CFTR F508del mutant (unknown origin) expressed in rat FRT cells assessed as Vmax preincubated for 18 to 24 hrs followed by compound wash out and subsequent compound and forskolin addition by fluorescence based assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Cystic fibrosis transmembrane conductance regulator(ALA4051)
Document: ALA4364316
Potentiator activity at CFTR F508del mutant (unknown origin) expressed in rat FRT cells assessed as Vmax preincubated for 18 to 24 hrs followed by compound wash out and subsequent compound and forskolin addition by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4368069
Vmax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 390.44 | 3.27 | 3.27 |
| 390.44 | 3.27 | 3.27 |
| 374.44 | 3.57 | 3.57 |
| 422.51 | 2.93 | 2.93 |
| 390.42 | 3.22 | 3.22 |
| 350.45 | 3.63 | 3.63 |