Basic Information
ID: ALA4368311
Type: Binding
Description: Inhibition of COX-1 in mouse J774 cells assessed as inhibition of PEG2 production using arachidonic acid as substrate pretreated for 15 mins followed by substrate addition measured after 30 mins by radioimmuno assay
Organism: Mus musculus
Cell type: J774
Activity Charts
Bioactivity
Activity Types for Assay ALA4368311
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 417.50 | 3.55 | 3.55 |
| 447.60 | 4.70 | 4.70 |
| 445.61 | 4.22 | 4.22 |
| 463.60 | 4.36 | 4.36 |
| 431.60 | 5.68 | 5.68 |
| 413.61 | 5.54 | 5.54 |
| 431.60 | 5.68 | 5.68 |
| 429.61 | 4.56 | 4.56 |