Basic Information
ID: ALA4368509
Type: Binding
Description: Inhibition of Lassa virus GPC expressed in recombinant vaccinia virus infected in African green monkey Vero cells assessed as reduction in GPC-mediated cell-cell fusion at 50 nM by beta-galactosidase reporter gene assay relative to control
Format: BAO_0000219
Organism: Mammarenavirus lassaense
Cell type: Vero
Target: Unchecked(ALA612545)
Document: ALA4364343
Inhibition of Lassa virus GPC expressed in recombinant vaccinia virus infected in African green monkey Vero cells assessed as reduction in GPC-mediated cell-cell fusion at 50 nM by beta-galactosidase reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4368509
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.52 | 3.58 | 3.58 |
| 522.57 | 5.60 | 5.60 |
| 523.56 | 5.15 | 5.15 |
| 442.56 | 4.49 | 4.49 |
| 570.61 | 6.42 | 6.42 |
| 496.53 | 5.20 | 5.20 |
| 556.63 | 6.79 | 6.79 |
| 564.68 | 5.77 | 5.77 |
| 519.57 | 5.60 | 5.60 |
| 453.54 | 4.05 | 4.05 |
| 473.53 | 4.09 | 4.09 |
| 470.61 | 5.30 | 5.30 |
| 550.50 | 6.09 | 6.09 |
| 458.56 | 4.19 | 4.19 |
| 538.57 | 5.24 | 5.24 |
| 428.53 | 4.18 | 4.18 |
| 444.53 | 3.89 | 3.89 |
| 446.51 | 4.92 | 4.92 |
| 460.53 | 3.59 | 3.59 |
| 492.54 | 5.83 | 5.83 |
| 510.56 | 5.59 | 5.59 |
| 533.59 | 5.99 | 5.99 |
| 509.57 | 5.26 | 5.26 |
| 508.54 | 5.30 | 5.30 |
| 500.95 | 5.84 | 5.84 |
| 458.56 | 4.19 | 4.19 |
| 460.53 | 3.59 | 3.59 |
| 524.54 | 5.12 | 5.12 |
| 442.56 | 4.49 | 4.49 |
| 496.53 | 5.20 | 5.20 |
| 508.54 | 5.30 | 5.30 |
| 444.53 | 3.89 | 3.89 |
| 517.55 | 5.74 | 5.74 |
| 616.52 | 7.16 | 7.16 |
| 564.65 | 4.94 | 4.94 |
| 467.49 | 4.59 | 4.59 |
| 506.52 | 5.94 | 5.94 |
| 536.55 | 5.95 | 5.95 |
| 511.50 | 5.10 | 5.10 |
| 534.66 | 5.76 | 5.76 |
| 520.63 | 5.97 | 5.97 |
| 496.53 | 5.20 | 5.20 |
| 564.68 | 5.77 | 5.77 |
| 479.58 | 4.73 | 4.73 |
| 442.56 | 4.22 | 4.22 |
| 504.63 | 5.85 | 5.85 |
| 517.55 | 5.74 | 5.74 |
| 460.53 | 3.59 | 3.59 |
| 474.63 | 4.90 | 4.90 |
| 556.65 | 5.64 | 5.64 |
| 505.54 | 5.67 | 5.67 |
| 510.56 | 5.13 | 5.13 |
| 538.57 | 5.18 | 5.18 |
| 496.53 | 4.83 | 4.83 |
| 514.98 | 5.77 | 5.77 |
| 517.55 | 5.74 | 5.74 |
| 471.60 | 4.25 | 4.25 |
| 531.58 | 5.93 | 5.93 |
| 535.57 | 5.68 | 5.68 |
| 453.54 | 4.05 | 4.05 |
| 429.52 | 3.58 | 3.58 |
| 508.62 | 5.34 | 5.34 |
| 496.53 | 5.20 | 5.20 |
| 466.50 | 5.19 | 5.19 |
| 446.52 | 4.32 | 4.32 |
| 496.53 | 4.68 | 4.68 |
| 474.63 | 4.90 | 4.90 |
| 478.59 | 5.33 | 5.33 |
| 454.57 | 4.69 | 4.69 |
| 474.56 | 3.90 | 3.90 |
| 496.53 | 4.83 | 4.83 |
| 530.59 | 6.27 | 6.27 |
| 488.58 | 4.20 | 4.20 |
| 429.52 | 3.58 | 3.58 |
| 462.98 | 4.83 | 4.83 |
| 520.63 | 5.97 | 5.97 |
| 468.48 | 3.98 | 3.98 |
| 573.66 | 5.52 | 5.52 |
| 621.70 | 6.24 | 6.24 |
| 484.62 | 5.40 | 5.40 |
| 518.54 | 5.13 | 5.13 |
| 478.98 | 4.54 | 4.54 |
| 454.57 | 4.67 | 4.67 |
| 480.97 | 4.97 | 4.97 |
| 484.49 | 5.33 | 5.33 |
| 494.56 | 5.81 | 5.81 |
| 484.49 | 5.33 | 5.33 |
| 533.59 | 5.61 | 5.61 |
| 522.59 | 6.41 | 6.41 |
| 478.59 | 5.33 | 5.33 |
| 509.57 | 5.26 | 5.26 |
| 462.98 | 4.83 | 4.83 |
| 453.54 | 4.05 | 4.05 |
| 458.56 | 4.19 | 4.19 |
| 473.53 | 4.09 | 4.09 |
| 456.59 | 4.61 | 4.61 |
| 446.52 | 4.32 | 4.32 |
| 505.54 | 5.67 | 5.67 |
| 516.56 | 6.34 | 6.34 |
| 534.50 | 6.21 | 6.21 |