Basic Information
ID: ALA4369190
Type: Functional
Description: Antitrypanosomal activity against Trypanosoma brucei brucei 427 bloodstream forms assessed as parasite viability at 10 uM after 24 hrs by resazurin dye based fluorescence assay relative to control
Organism: Trypanosoma brucei brucei
Strain: 427
Activity Charts
Bioactivity
Activity Types for Assay ALA4369190
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 309.33 | 4.44 | 4.44 |
| 403.27 | 4.53 | 4.53 |
| 403.27 | 4.13 | 4.13 |
| 396.95 | 3.15 | 3.15 |
| 359.82 | 3.08 | 3.08 |
| 306.37 | 3.94 | 3.94 |
| 263.30 | 3.29 | 3.29 |
| 410.54 | 4.64 | 4.64 |
| 320.39 | 4.76 | 4.76 |
| 320.40 | 3.28 | 3.28 |
| 474.57 | 2.64 | 2.64 |
| 371.47 | 3.38 | 3.38 |
| 294.40 | 4.16 | 4.16 |
| 372.47 | 3.94 | 3.94 |
| 370.43 | 3.12 | 3.12 |
| 394.92 | 3.97 | 3.97 |
| 429.55 | 5.35 | 5.35 |
| 291.40 | 4.01 | 4.01 |
| 332.37 | 2.46 | 2.46 |
| 309.39 | 3.11 | 3.11 |
| 449.62 | 4.02 | 4.02 |
| 260.30 | 3.13 | 3.13 |
| 432.92 | 3.71 | 3.71 |
| 460.59 | 2.57 | 2.57 |
| 330.56 | 4.68 | 4.68 |
| 335.37 | 1.51 | 1.51 |
| 495.44 | 3.62 | 3.62 |
| 297.33 | 3.43 | 3.43 |
| 254.27 | 0.07 | 0.07 |
| 325.39 | 3.61 | 3.61 |
| 397.95 | 4.69 | 4.69 |
| 308.41 | 3.78 | 3.78 |
| 329.36 | 3.36 | 3.36 |
| 326.79 | 3.79 | 3.79 |
| 419.37 | 4.75 | 4.75 |
| 383.48 | 3.11 | 3.11 |
| 347.40 | 3.64 | 3.64 |
| 377.49 | 3.46 | 3.46 |
| 320.33 | 4.14 | 4.14 |
| 426.52 | 3.78 | 3.78 |
| 546.67 | 5.41 | 5.41 |
| 383.68 | 5.34 | 5.34 |
| 584.72 | 5.96 | 5.96 |
| 321.06 | ||
| 401.45 | 5.06 | 5.06 |
| 365.45 | 3.94 | 3.94 |
| 312.34 | 2.07 | 2.07 |
| 313.79 | 3.53 | 3.53 |
| 337.38 | 3.25 | 3.25 |
| 458.54 | 2.16 | 2.16 |
| 269.30 | 2.68 | 2.68 |
| 232.24 | 2.10 | 2.10 |
| 354.39 | 3.33 | 3.33 |
| 297.40 | 3.11 | 3.11 |
| 331.39 | 3.61 | 3.61 |
| 490.59 | 3.33 | 3.33 |
| 474.59 | 3.63 | 3.63 |
| 424.93 | 4.19 | 4.19 |
| 422.33 | 3.28 | 3.28 |
| 534.52 | 2.95 | 2.95 |
| 276.36 | 3.40 | 3.40 |
| 330.39 | 4.25 | 4.25 |
| 495.01 | 4.02 | 4.02 |
| 449.77 | 5.83 | 5.83 |
| 437.50 | 2.38 | 2.38 |
| 609.21 | ||
| 325.48 | 3.87 | 3.87 |
| 461.52 | 3.43 | 3.43 |
| 343.90 | 5.10 | 5.10 |