Basic Information
ID: ALA4369200
Type: Binding
Description: Inhibition of HIV1 subtype C recombinant integrase strand transfer activity preincubated for 45 mins with double-stranded biotinylated donor DNA followed by addition of double stranded FITC-labelled target DNA and measured after 60 mins relative to control
Format: BAO_0000357
Organism: Human immunodeficiency virus 1
Strain: subtype C
Target: Human immunodeficiency virus type 1 integrase(ALA3471)
Document: ALA4368863
Inhibition of HIV1 subtype C recombinant integrase strand transfer activity preincubated for 45 mins with double-stranded biotinylated donor DNA followed by addition of double stranded FITC-labelled target DNA and measured after 60 mins relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4369200
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 474.37 | 1.23 | 1.23 |
| 384.34 | 1.59 | 1.59 |
| 437.63 | 2.99 | 2.99 |
| 388.76 | 2.24 | 2.24 |
| 433.21 | 2.34 | 2.34 |
| 354.32 | 1.58 | 1.58 |
| 398.37 | 1.98 | 1.98 |
| 358.74 | 2.23 | 2.23 |
| 324.29 | 1.57 | 1.57 |
| 402.79 | 2.63 | 2.63 |
| 368.35 | 1.97 | 1.97 |
| 358.74 | 2.23 | 2.23 |
| 388.76 | 2.24 | 2.24 |
| 403.19 | 2.34 | 2.34 |
| 393.18 | 2.88 | 2.88 |
| 354.32 | 1.58 | 1.58 |