Basic Information
ID: ALA4370147
Type: Binding
Description: Inhibition of PIM1/PIM2/PIM3 in human KMS-12-BM cells assessed as reduction in BAD phosphorylation after 110 mins by flow cytometric analysis
Organism: Homo sapiens
Cell type: KMS-12-BM
Activity Charts
Bioactivity
Activity Types for Assay ALA4370147
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 391.48 | 3.74 | 3.74 |
| 393.49 | 3.99 | 3.99 |
| 363.42 | 2.70 | 2.70 |
| 389.46 | 3.50 | 3.50 |
| 365.44 | 2.94 | 2.94 |
| 403.49 | 3.57 | 3.57 |
| 407.52 | 4.16 | 4.16 |
| 405.50 | 3.82 | 3.82 |
| 464.57 | 2.74 | 2.74 |
| 422.53 | 3.14 | 3.14 |
| 419.49 | 2.69 | 2.69 |
| 457.54 | 3.50 | 3.50 |
| 405.50 | 3.92 | 3.92 |
| 435.53 | 3.59 | 3.59 |
| 457.54 | 3.50 | 3.50 |
| 459.55 | 3.75 | 3.75 |
| 420.52 | 2.90 | 2.90 |
| 403.49 | 3.89 | 3.89 |
| 457.54 | 3.50 | 3.50 |
| 421.50 | 3.05 | 3.05 |
| 464.57 | 2.74 | 2.74 |
| 418.50 | 2.65 | 2.65 |
| 435.53 | 3.59 | 3.59 |
| 445.53 | 3.19 | 3.19 |
| 403.49 | 3.67 | 3.67 |
| 405.50 | 3.92 | 3.92 |
| 421.50 | 2.93 | 2.93 |