Basic Information
ID: ALA4370605
Type: Binding
Description: Inhibition of HIF1alpha transcriptional activity in human Hep3B cells after 24 hrs in hypoxic condition by HRE-dual luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Hypoxia-inducible factor 1 alpha(ALA4261)
Document: ALA4368925
Inhibition of HIF1alpha transcriptional activity in human Hep3B cells after 24 hrs in hypoxic condition by HRE-dual luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4370605
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.71 | 7.09 | 7.09 |
| 633.32 | 8.91 | 8.91 |
| 598.88 | 8.26 | 8.26 |
| 635.34 | 8.88 | 8.88 |
| 669.78 | 9.53 | 9.53 |
| 604.91 | 8.32 | 8.32 |
| 588.84 | 7.85 | 7.85 |
| 633.32 | 8.91 | 8.91 |
| 616.87 | 8.40 | 8.40 |
| 527.82 | 6.92 | 6.92 |
| 648.94 | 9.41 | 9.41 |
| 616.87 | 8.40 | 8.40 |
| 614.92 | 8.53 | 8.53 |
| 677.77 | 9.02 | 9.02 |
| 510.77 | 6.57 | 6.57 |
| 667.77 | 9.57 | 9.57 |
| 635.34 | 8.88 | 8.88 |
| 633.32 | 8.91 | 8.91 |
| 538.82 | 7.05 | 7.05 |
| 524.79 | 6.66 | 6.66 |
| 677.77 | 9.02 | 9.02 |
| 669.78 | 9.53 | 9.53 |
| 618.88 | 8.37 | 8.37 |
| 616.87 | 8.40 | 8.40 |
| 667.77 | 9.57 | 9.57 |
| 612.90 | 8.57 | 8.57 |
| 580.90 | 8.22 | 8.22 |
| 511.75 | 6.75 | 6.75 |
| 643.87 | 8.17 | 8.17 |