Assay Report Card

Basic Information

ID: ALA4370818

Type: Binding

Description: Inhibition of Leucyl-tRNA synthetase-mediated mTORC1 signaling activation in human HEK293 cells assessed as reduction in leucine-induced S6K phosphorylation preincubated for 50 mins followed by leucine-stimulation and measured after 10 mins by Western blot analysis

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
460.47-2.19-2.19
460.47-2.19-2.19