Basic Information
ID: ALA4370820
Type: Binding
Description: Inhibition of mTORC2 signaling in human HEK293 cells assessed as reduction in leucine-induced AKT phosphorylation at 200 uM preincubated for 50 mins followed by leucine-stimulation and measured after 10 mins by Western blot analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4370820
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 476.47 | -3.22 | -3.22 |
| 460.47 | -2.19 | -2.19 |
| 444.47 | -1.16 | -1.16 |
| 602.36 | -2.61 | -2.61 |
| 490.50 | -2.76 | -2.76 |
| 488.52 | -1.07 | -1.07 |
| 444.47 | -1.16 | -1.16 |
| 460.47 | -2.19 | -2.19 |
| 476.47 | -3.22 | -3.22 |
| 460.47 | -2.19 | -2.19 |