Basic Information
ID: ALA4370867
Type: Binding
Description: Inhibition of human TDO expressed in Escherichia coli at 10 uM using L-tryptophan as substrate after 1 hr by UV absorption analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: Tryptophan 2,3-dioxygenase(ALA2140)
Document: ALA4368939
Inhibition of human TDO expressed in Escherichia coli at 10 uM using L-tryptophan as substrate after 1 hr by UV absorption analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4370867
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 318.17 | 3.64 | 3.64 |
| 336.16 | 3.78 | 3.78 |
| 333.19 | 3.74 | 3.74 |
| 331.22 | 3.56 | 3.56 |
| 361.20 | 4.03 | 4.03 |
| 308.20 | 4.00 | 4.00 |
| 361.20 | 4.41 | 4.41 |
| 332.20 | 3.95 | 3.95 |
| 316.20 | 4.50 | 4.50 |
| 367.25 | 4.67 | 4.67 |
| 317.19 | 3.52 | 3.52 |
| 317.19 | 3.52 | 3.52 |
| 358.26 | 5.15 | 5.15 |
| 317.19 | 3.52 | 3.52 |
| 381.26 | 2.58 | 2.58 |
| 333.19 | 3.74 | 3.74 |
| 333.19 | 3.23 | 3.23 |
| 292.14 | 2.66 | 2.66 |
| 464.37 | 4.74 | 4.74 |
| 334.17 | 3.35 | 3.35 |
| 327.19 | 3.81 | 3.81 |
| 292.14 | 3.53 | 3.53 |
| 352.62 | 4.30 | 4.30 |
| 346.18 | 3.67 | 3.67 |
| 332.20 | 3.95 | 3.95 |
| 318.17 | 3.64 | 3.64 |
| 458.36 | 4.28 | 4.28 |
| 413.32 | 4.86 | 4.86 |
| 332.20 | 3.43 | 3.43 |
| 334.17 | 3.35 | 3.35 |
| 415.34 | 4.65 | 4.65 |
| 254.13 | 3.15 | 3.15 |
| 303.16 | 3.33 | 3.33 |
| 324.21 | 2.98 | 2.98 |
| 344.17 | 3.47 | 3.47 |
| 336.16 | 3.78 | 3.78 |
| 370.17 | 4.96 | 4.96 |
| 389.25 | 4.51 | 4.51 |
| 359.23 | 3.90 | 3.90 |