Basic Information
ID: ALA4370954
Type: Binding
Description: Protac activity against VHL/cullin2/ERalpha in human MCF7 cells assessed as ERalpha degradation by measuring ER protein/GADPH ratio at 1 nM after 4 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: MCF7
Activity Charts
Bioactivity
Activity Types for Assay ALA4370954
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 458.65 | 5.85 | 5.85 |
| 1042.38 | ||
| 929.19 | 8.60 | 8.60 |
| 1016.34 | ||
| 961.28 | 9.92 | 9.92 |
| 930.18 | 8.49 | 8.49 |
| 1057.39 | ||
| 974.26 | 9.27 | 9.27 |
| 947.25 | 9.75 | 9.75 |
| 946.20 | 8.49 | 8.49 |
| 1058.38 | ||
| 988.29 | 9.66 | 9.66 |
| 988.29 | 9.66 | 9.66 |
| 1030.37 | ||
| 940.31 | 10.90 | 10.90 |
| 945.24 | 9.50 | 9.50 |
| 1016.34 | ||
| 988.29 | 9.49 | 9.49 |
| 1042.38 | ||
| 939.62 | 9.28 | 9.28 |
| 1036.29 | ||
| 1056.40 | ||
| 1014.32 | ||
| 1020.28 | ||
| 956.31 | 10.10 | 10.10 |
| 985.30 | 9.92 | 9.92 |
| 1002.31 | ||
| 1040.32 | ||
| 1064.34 | ||
| 1028.35 | ||
| 1006.26 | ||
| 956.31 | 10.60 | 10.60 |
| 1030.37 | ||
| 1004.28 | ||
| 1064.34 | ||
| 960.23 | 8.88 | 8.88 |