Assay Report Card

Basic Information

ID: ALA4370957

Type: Binding

Description: Protac activity against VHL/cullin2/ERalpha in human MCF7 cells assessed as ERalpha degradation by measuring ER protein/GADPH ratio at 1000 nM after 4 hrs by Western blot analysis relative to control

Organism: Homo sapiens

Cell type: MCF7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1002.31
1064.34
1004.28