Basic Information
ID: ALA4371708
Type: Binding
Description: Inhibition of human 20S proteasome chymotrypsin-like activity using Suc-Leu-Leu-Val-Tyr-AMC as substrate pretreated for 15 mins followed by substrate addition by fluorescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Proteasome Macropain subunit MB1(ALA4662)
Document: ALA4371012
Inhibition of human 20S proteasome chymotrypsin-like activity using Suc-Leu-Leu-Val-Tyr-AMC as substrate pretreated for 15 mins followed by substrate addition by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4371708
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 532.62 | 0.41 | 0.41 |
| 569.66 | 0.79 | 0.79 |
| 583.69 | 1.18 | 1.18 |
| 625.72 | 1.98 | 1.98 |
| 596.68 | 1.37 | 1.37 |
| 596.68 | 1.37 | 1.37 |
| 568.67 | 1.39 | 1.39 |
| 595.69 | 1.97 | 1.97 |
| 616.74 | 1.74 | 1.74 |
| 583.64 | 0.43 | 0.43 |
| 637.77 | 3.14 | 3.14 |
| 630.14 | 2.62 | 2.62 |
| 630.14 | 2.62 | 2.62 |
| 623.75 | 2.75 | 2.75 |
| 586.69 | 0.27 | 0.27 |
| 583.69 | 0.87 | 0.87 |
| 569.66 | 0.79 | 0.79 |
| 579.69 | 2.73 | 2.73 |
| 609.72 | 2.28 | 2.28 |
| 593.72 | 3.12 | 3.12 |
| 601.72 | 2.03 | 2.03 |
| 627.69 | 0.44 | 0.44 |
| 583.69 | 1.18 | 1.18 |
| 613.68 | 2.11 | 2.11 |
| 599.69 | 0.70 | 0.70 |
| 609.72 | 2.36 | 2.36 |
| 567.64 | 1.19 | 1.19 |
| 625.72 | 1.98 | 1.98 |
| 581.67 | 1.58 | 1.58 |
| 613.68 | 2.11 | 2.11 |
| 623.75 | 2.75 | 2.75 |